Betaine Anhydrous is a natural compound that is found in the body and in sugar beets, which is the basis of the name 'betaine'. Betaine is also known as and referred to as Trimethylglycine or TMG for short.

Betaine is a small trimethylated amino acid with glycine being the amino acid element, therefore giving it the name Trimethyl-glycine. Betaine Anhydrous, Trimethylglycine, and TMG are the exact same ingredient, with no variance whatsoever based on the name choice shown on a product ingredient panel. Sometimes you may see products that use Betaine Nitrate which is Betaine Anhydrous paired with a Nitrate for additional benefits.

Betaine plays a few roles in the body but is most known in the sports supplements industry for providing similar benefits to creatine. In simple terms, betaine works as an osmolyte in the body, just like creatine. Osmolytes are molecules that are moved in and out of cells in order to maintain cell volume and fluid balance. A better-hydrated cell is more resilient to stressors such as training and exercise.

Betaine serves a vital role in methylation in the body. It does this through two possible mechanisms: either being used as a methyl donor to reduce homocysteine into the amino acid L-methionine or by increasing levels of active folate molecules which then go on to donate methyl groups and reduce homocysteine levels through the methylation process.

So why is all this improved methylation important? It's all comes down to an amino acid called homocysteine. Homocysteine is produced in the body from the breakdown of proteins as part of the methylation process. High levels of homocysteine are increasingly being recognised as an important risk factor for disease and seen as an indicator of potential health problems such as cardiovascular disease and alzheimers.

Betaine supplementation has been studied to have positive effects on muscular power, muscular endurance & body composition.

How to consume

A minimum of 2.5g per day has been shown to yield the body composition changing results from the studies above. The studies supplemented betaine in both a single 2.5g dose per day and also a 1.25g dose, twice per day. It is not clear whether there is any benefit to how you ingest the 2.5g serve.